AI to Show Promising Results in Predicting Chronic, Under Diagnosed, Conditions from Standard CT Scans

Zebra Medical Vision and Clalit Health Services Complete Two Groundbreaking Research Projects, Showing How AI Can Be Used to Predict Under Diagnosed Chronic Conditions. the Research Projects Will Be Presented During RSNA 2018.

Zebra Medical Vision and Clalit Health Services announce the completion of two groundbreaking research projects that allow early identification of patients with bone and cardiovascular disease. Using existing CT data, Zebra-Med’s algorithms allow Clalit to identify patients at risk of Osteoporotic fractures and Cardiac events. Both research projects were independently validated by the Clalit Research Institute and will be presented for the first time during RSNA. Clalit owns and operates 1,500 primary care clinics and 14 hospitals, including 30% of Israel’s hospital acute care beds, treating over 4 million patients.

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“As more nations and health providers move toward value-based healthcare, we are encouraged by these two groundbreaking research projects that show the power of AI and retrospective analysis of existing scans”

 

Research #1: “Automatic evaluation of CT scans for prediction of Osteoporotic Fractures”

In one of the largest Osteoporosis experiments completed to date, a retrospective cohort of 48,227 individuals with Abdominal CT studies, ages 50-90, was studied over five years from the point of CT imaging to assess risk factors for the incidence of major and hip-specific osteoporotic fractures. The results showed that a combination of automatic Zebra-Med algorithms achieved equivalent risk-stratification compared with the contemporary FRAX scoring system. In addition, the research showed that the addition of Zebra-Med’s risk score to FRAX achieved results superior to those of FRAX alone.

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Potential Applications: If applied routinely to all CT studies of chest or abdomen, this would immediately stratify risks of osteoporotic fractures for all individuals over age 50. This would lead to secondary work up and possible prophylactic treatment. Currently, fewer than 20% of those at risk undergo routine screening but over 66% undergo routine CT studies, illustrating the dramatic potential to increase awareness and prophylactic treatment in this growing population. Osteoporosis fractures cost $18B per year to the US healthcare system and $3B to the UK NHS.

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